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2008-2013年  南京農(nóng)業(yè)大學(xué)預(yù)防獸醫(yī)學(xué)，博士學(xué)位 

2014- 2017 濱州醫(yī)學(xué)院代謝與神經(jīng)精神疾病研究所，講師

2017-2019，美國佐治亞州奧古斯塔大學(xué)（Augusta university）佐治亞醫(yī)學(xué)院神經(jīng)與再生醫(yī)學(xué)系，博士后

2019-，濱州醫(yī)學(xué)院代謝與神經(jīng)精神疾病研究所，講師

研究方向：博士期間研究宿主細(xì)胞RNA解旋酶在病毒感染中作用機(jī)制，涉及研究領(lǐng)域包括病毒學(xué)、細(xì)胞分子生物學(xué)及蛋白質(zhì)結(jié)構(gòu)生物學(xué)。目前研究課題為慢性應(yīng)激所致抑郁障礙的表觀遺傳學(xué)。

代表論著：

1.     Chen Li*, Fantao Meng, Jacob C Garza, Jing Liu, Yun Lei, Sergei A Kirov, Ming Guo, Xin-Yun Lu*. Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons. 2020, Molecular psychiatry, doi: 10.1038/ s41380-020-0649-0.

2.     Ming Guo, Chen Li, Yun Lei, Shengmin Xu, Di Zhao, Xin-Yun Lu*. Role of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/ anxiety-related behaviors. Molecular psychiatry, 2017, 22(7):1056-1068.

3.     Yun Lei, Jian-gong Wang, Dan Wang, Chen Li, Bin Liu, Xing Fang, Jing-jing You, Ming Guo, Xin-Yun Lu*. SIRT1 in forebrain excitatory neurons produces sexually dimorphic effects on depression-related behaviors and modulates neuronal excitability and synaptic transmission in the medial prefrontal cortex. 2019, Molecular psychiatry, doi: 10.1038/s41380-019-0352-1.

4.     Feng-jiao Sun, Yun Lei, Jing-jing You, Chen Li, Lin-shan Sun, Jacob Garza, Di Zhang, Ming Guo, Phillip E Scherer, Daniel Lodge, Xin-Yun Lu*. Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1. Molecular psychiatry, 2019 Jan;24(1):126-144.

5.     Chen Li*, Ling-ling Ge, Peng-peng Li, Yue Wang, Juan-juan Dai, Ming-xia Sun, Li Huang, Zhi-qiang Shen, Xiao-chun Hu, Hassan Ishag, Xiang Mao*. Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions. Virology, 2014, 44, (9),70-81.

6.     Chen Li, Ling-ling Ge, Ya-ling Yu, Li Huang, Yue Wang, Ming-xia Sun, Hassan Ishag, Liang-xiao Ma, Xue-hua Li, Zhi-qiang Shen*, Xiang Mao*. A tripeptide (NSK) inhibits Japanese encephalitis virus infection in vitro and in vivo. Archives of Virology, 2014.159(5):1045-1055.

7.     Chen Li, Ling-ging Ge, Peng-peng Li, Yue Wang, Ming-xia Sun, Li Huang, Hassan Ishag, Dong-dong Di, Zhi-qiang Shen, Wei-xing Fan*, Xiang Mao*. The DEAD-box RNA helicase DDX5 acts as a positive regulator of Japanese encephalitis virus replication by binding to viral 3' UTR. Antiviral Research, 2013, 100, (2), 487-499.

8.     Chen Li, Li-ying Zhang, Peng-peng Li, Ming-Xia Sun, Li Huang, Jian-chao Wei, Yi-lin Yao, Hassan Ishag, Pu-yan Chen*, Xiang Mao*. Inhibition of Japanese Encephalitis Virus Entry into the Cells by the Envelope glycoprotein Domain III (EDIII) and the Loop 3 Peptide Derived From EDIII. Antiviral Research, 2012, 94(2):179-183.

9.     Hassan. A. Ishag, Chen Li, Li, Huang, Ming-xia Sun, Fang quan Wang, Bo Ni, Pu-yan Chen, Xiang Mao*. Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivo. Archives of Virology, 2013, 158(2):349-358.

10.  Hassan Z.A. Ishag, Chen Li, Li Huang, Xiang Mao*. 2012. Inhibition of Japanese encephalitis virus infection in vitro and in vivo by Pokeweed Antiviral Protein. Virus Research, 2013, 171(1):89-96.

11.  Hassan Ishag*, Chen Li, Fengjuan Wang, Xiang Mao*, Griffithsin binds to the glycosylated proteins (E and prM) of Japanese encephalitis virus and inhibit its infection. Virus Research, 2016, 215: 50-54.

12.  Ming-xia Sun, Li Huang, Rui Wang, Ya-ling Yu, Chen Li, Peng-peng Li, Xiang Mao*. Porcine Reproductive and Respiratory syndrome Virus Induce Autophagy to Promote Virus Replication. Autophagy.2012, 1; 8(10):1434-47.

13.  Li Huang, Yuan-peng Zhang, Ya-ling Yu, Ming-xia Sun, Chen Li, Bo Ni, Xiu-hua Wang, Pu-yan Chen, Xiang Mao*. Role of cholesterol in porcine reproductive and respiratory syndrome virus (PRRSV) infection on MARC-145 cells. Biochemical and Biophysical Research Communications, 2011,414:545-550.

14.  Yue Wang, Jia-rong Li, Ming-xia Sun, Bo Ni, Chang-chao Huan, Li Huang, Chen Li, Fan Hong-jie, Xiao-feng Ren*, Xiang Mao*. Antiviral Research.2014, 106 :33-41.

承擔(dān)課題：

1.國家自然科學(xué)基金項(xiàng)目：中縫背核5-HT神經(jīng)元中AdipoR1對(duì)應(yīng)激易感性和抑郁行為調(diào)控的研究（81601189）。立項(xiàng)時(shí)間：2017-2019年，負(fù)責(zé)人：李晨。

2.山東省自然科學(xué)基金青年基金項(xiàng)目：瘦素對(duì)BDNF基因轉(zhuǎn)錄的表觀遺傳學(xué)調(diào)控在其抗抑郁機(jī)制中的作用（ZR2014HQ080）。立項(xiàng)時(shí)間：2014-2016年，負(fù)責(zé)人：李晨。